Hereditary transthyretin (hATTR) amyloidosis is a rare disease that runs in families. It is caused by the buildup of toxic proteins called amyloid fibrils throughout the body. The amyloid fibrils damage tissues and organs, causing symptoms that worsen over time.
The most common sites of amyloid buildup in hATTR amyloidosis are nerves and the heart. Other targeted areas include the stomach, intestines, eyes, kidneys, brain, and spinal cord.
This article reviews the symptoms and signs of hATTR amyloidosis. Early recognition of this incurable disease is crucial to preventing or delaying disease progression and potentially life-threatening complications.
Hereditary transthyretin (hATTR) amyloidosis is a rare disease that runs in families. It is caused by the buildup of toxic proteins called amyloid fibrils throughout the body. The amyloid fibrils damage tissues and organs, causing symptoms that worsen over time.
The most common sites of amyloid buildup in hATTR amyloidosis are nerves and the heart. Other targeted areas include the stomach, intestines, eyes, kidneys, brain, and spinal cord.
This article reviews the symptoms and signs of hATTR amyloidosis. Early recognition of this incurable disease is crucial to preventing or delaying disease progression and potentially life-threatening complications.
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